Renal-artery denervation did not result in a significant reduction of systolic blood pressure compared to sham control in patients with resistant hypertension after 6 months.
Does renal-artery denervation reduce systolic blood pressure in patients with resistant hypertension?
Patients with resistant hypertension
Renal-artery denervation
Sham control
Reduction of systolic blood pressure at 6 monthssurrogate
Renal-artery denervation failed to significantly reduce systolic blood pressure compared to a sham procedure in patients with resistant hypertension.
This blinded trial did not show a significant reduction of systolic blood pressure in patients with resistant hypertension 6 months after renal-artery denervation as compared with a sham control. (Funded by Medtronic; SYMPLICITY HTN-3 ClinicalTrials.gov number, NCT01418261.).
“A decade later, renal denervation has re-emerged with stronger evidence, refined technique and renewed clinical relevance.”
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Deepak L. Bhatt
David E. Kandzari
William W. O’Neill
New England Journal of Medicine
Harvard University
University of Pennsylvania
University of Chicago
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Bhatt et al. (Sat,) reported a other. Renal-artery denervation did not result in a significant reduction of systolic blood pressure compared to sham control in patients with resistant hypertension after 6 months.
www.synapsesocial.com/papers/697e18711f386ba20591f0d5 — DOI: https://doi.org/10.1056/nejmoa1402670