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A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright-Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models.
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Richard R. Hudson (Fri,) studied this question.
www.synapsesocial.com/papers/69d9614704deaa6ab568435d — DOI: https://doi.org/10.1093/bioinformatics/18.2.337
Richard R. Hudson
Bioinformatics
University of Chicago
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