Does multiplexed real-time PCR allow simultaneous screening for SMA and SCID from a single newborn dried blood spot punch?
A multiplexed real-time PCR assay allows for the simultaneous newborn screening of SMA and SCID from a single dried blood spot.
SMA caused by the absence of SMN1 can be detected from the same DBS punch used to screen newborns for SCID.
Taylor et al. (Fri,) studied this question.