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SLiM is an efficient forward population genetic simulation designed for studying the effects of linkage and selection on a chromosome-wide scale. The program can incorporate complex scenarios of demography and population substructure, various models for selection and dominance of new mutations, arbitrary gene structure, and user-defined recombination maps.
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Philipp W. Messer (Sat,) studied this question.
www.synapsesocial.com/papers/6a12edb15bb7edc7189e7b49 — DOI: https://doi.org/10.1534/genetics.113.152181
Philipp W. Messer
Genetics
Stanford University
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