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The authors have developed an MG activities of daily living (ADL) profile (MG-ADL)-a simple eight-question survey of MG symptoms. In 254 consecutive encounters with established MG patients, the authors compared scores from the MG-ADL to the quantitative MG score (QMG)-a standardized, reliable scale used in clinical trials. The mean MG-ADL score was 4.89+/-3.63. The mean QMG score was 10.80+/-5.70. Pearson's correlation coefficient was 0.583 (p < 0.001). The MG-ADL is an easy-to-administer survey of MG that correlates well with the QMG and can serve as a secondary efficacy measurement in clinical trials.
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Gil I. Wolfe
University at Buffalo, State University of New York
Laura Herbelin
University of Missouri
Sharon Nations
University of North Carolina at Chapel Hill
Neurology
American Academy of Neurology
Advanced Projects Research Incorporated (United States)
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Wolfe et al. (Thu,) studied this question.
synapsesocial.com/papers/69dabd0937b5141e3ba3c627 — DOI: https://doi.org/10.1212/wnl.52.7.1487
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