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In vivo NMR has focused on using 31P and 1H to study metabolism in humans. Comparable 13C NMR studies have not been undertaken, presumably, because of its insensitivity. We report herein that the natural abundance 13C signal from C1 glycogen is observable. The ability to observe the signal opens new opportunities to noninvasively study glycogen metabolism in man.
Jue et al. (Thu,) studied this question.