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Cells organize many of their biochemical reactions in non-membrane compartments. Recent evidence has shown that many of these compartments are liquids that form by phase separation from the cytoplasm. Here we discuss the basic physical concepts necessary to understand the consequences of liquid-like states for biological functions.
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Anthony A. Hyman
Christoph A. Weber
Frank Jülicher
Annual Review of Cell and Developmental Biology
Max Planck Society
Max Planck Institute of Molecular Cell Biology and Genetics
Max Planck Institute for the Physics of Complex Systems
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Hyman et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d83910617ce96c42ae33d0 — DOI: https://doi.org/10.1146/annurev-cellbio-100913-013325