High-risk cardiac patients
Presence of inflammatory mediators in epicardial adipose tissuesurrogate
Local inflammation in epicardial adipose tissue is not reflected by systemic biomarkers or eliminated by current therapies in high-risk cardiac patients.
Epicardial adipose tissue is a source of several inflammatory mediators in high-risk cardiac patients. Plasma inflammatory biomarkers may not adequately reflect local tissue inflammation. Current therapies do not appear to eliminate local inflammatory signals in epicardial adipose tissue.
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Tomasz Mazurek
Lifeng Zhang
Andrew Zalewski
Circulation
GlaxoSmithKline (United States)
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Mazurek et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d893b58c03fbaff8bef795 — DOI: https://doi.org/10.1161/01.cir.0000099542.57313.c5