May 1, 2001Open Access
View Full PaperChanges in Cardiovascular Risk Factors During the Perimenopause and Postmenopause and Carotid Artery Atherosclerosis in Healthy Women
Structured PICO
Do premenopausal levels of cardiovascular risk factors predict the need for intervention in midlife women?
P
Population
Healthy women in perimenopause and postmenopause
O
Outcome
Changes in cardiovascular risk factors and carotid artery atherosclerosissurrogate
Premenopausal cardiovascular risk factor levels can effectively identify women who require targeted interventions during and after menopause.
Abstract
Absolute risk for cardiovascular disease increases substantially in midlife, with a particularly adverse effect on lipid metabolism at the menopause. Premenopausal levels of risk factors are adequate to identify which women should be targeted for intervention.