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May 12, 2011Open Access

Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4

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Abstract

Colocalization and staining patterns of metabolic and hypoxia-related proteins provides valuable additional information over single protein analyses and can improve the understanding of their functions and environmental influences.

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Authors

Saskia E. Rademakers

Leiden University Medical Center

Jasper Lok

Radboud University Nijmegen

Albert J. van der Kogel

Amgen (United States)

Journals

SHILAP Revista de lepidopterología

BMC Cancer

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Institutions

Radboud University Nijmegen

Radboud University Medical Center

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Rademakers et al. (Thu,) studied this question.

synapsesocial.com/papers/69d9e6435e5bcb4e3b838322 — DOI: https://doi.org/10.1186/1471-2407-11-167

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Neuronal functions, feeding behavior, and energy balance inSlc2a3+/−mice· 2008 · 34 citations
LOUIS PASTEUR. ACHIEVEMENTS AND DISAPPOINTMENTS, 1861· 1961 · 44 citations
Cancer's Molecular Sweet Tooth and the Warburg Effect· 2006 · 1,219 citations
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice· 2008 · 1,609 citations
Hypoxia induced expression of endogenous markers in vitro is highly influenced by pH· 2007 · 63 citations

Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4

Key Points

Abstract

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Discussion

Authors

Journals

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Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study

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