July 4, 2013Open Access
Relationship between Intraoperative Mean Arterial Pressure and Clinical Outcomes after Noncardiac Surgery
Structured PICO
Is an intraoperative MAP less than 55 mmHg associated with AKI and myocardial injury in patients undergoing noncardiac surgery?
P
Population
Patients undergoing noncardiac surgery
I
Intervention
Intraoperative mean arterial pressure (MAP) less than 55 mmHg
O
Outcome
Acute kidney injury (AKI) and myocardial injuryhard clinical
Maintaining intraoperative MAP above 55 mmHg during noncardiac surgery may be important to prevent acute kidney injury and myocardial injury, though randomized trials are needed.
Abstract
Even short durations of an intraoperative MAP less than 55 mmHg are associated with AKI and myocardial injury. Randomized trials are required to determine whether outcomes improve with interventions that maintain an intraoperative MAP of at least 55 mmHg.