What are the microvascular effects of insulin resistance and diabetes on cardiac structure, function, and perfusion?
Patients with diabetes and insulin resistance
Cardiac structure, function, and perfusion (LV mass, LV torsion, and myocardial perfusion reserve [MPR])surrogate
Diabetes is associated with adverse changes in cardiac structure and microvascular perfusion, suggesting a mechanistic link between microvascular disease and cardiac dysfunction.
Patients with diabetes have increased LV mass, LV torsion, and decreased MPR. There is a significant association between decreased MPR and increased LV torsion suggesting a possible mechanistic link between microvascular disease and cardiac dysfunction in diabetes.
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Adbul Larghat
University of Leeds
Peter Swoboda
Cardiac Imaging
John Biglands
Leeds General Infirmary
European Heart Journal - Cardiovascular Imaging
University of Leeds
University of Tripoli
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Larghat et al. (Tue,) studied this question.
synapsesocial.com/papers/69d56fad75589c71d767da76 — DOI: https://doi.org/10.1093/ehjci/jeu142