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The effect of conventional propranolol and bendrofluazide tablets given twice daily has been compared with an equivalent dosage combined in a single capsule given twice daily in fourteen patients with essential hypertension. Good blood pressure control was achieved on both regimes in the majority of patients and there was no significant difference in treatment response between the two regimes. Use of the combined capsule is convenient and may improve patient compliance.
Solomon et al. (Tue,) studied this question.