High ACEF and Clinical SYNTAX scores predicted higher 1-year MACE rates (24% vs 9%, P=0.017 for ACEF; 25% vs 8%, P=0.008 for CSS) in patients undergoing rotational atherectomy with stenting.
Cohort (n=221)
Do ACEF and Clinical SYNTAX scores predict 1-year MACE in patients with heavily calcified coronary stenosis undergoing rotational atherectomy with stent implantation?
Both ACEF and Clinical SYNTAX scores provide moderate predictive accuracy for 1-year MACE in patients undergoing rotational atherectomy for heavily calcified coronary stenosis.
Absolute Event Rate: 24% vs 9%
p-value: p=0.017
AIM: To assess ACEF (age, creatinine, and ejection fraction) and Clinical SYNTAX (CSS) score in the risk stratification of patients with heavily calcified stenosis undergoing rotational atherectomy with stent implantation (rota-stenting). METHODS AND RESULTS: ACEF and CSS were calculated in 221 consecutive patients with stable angina undergoing rota-stenting. Mean age of the patients was 74 ± 10 years, left ventricular ejection fraction was 61 ± 18%, and final burr size 1.78 ± 0.24 mm, with 2.6 ± 0.9 burrs used for each patient. Primary end-point was MACE at one-year defined as the composite of cardiac death, myocardial infarction, and target vessel revascularization. Post-hoc analysis was performed by stratifying the clinical outcome according to ACEF and CSS tertiles. At 1 year there was a significantly higher MACE rate in the high tertile of ACEF (24% for ACEFHigh vs. 13% for ACEFMid vs. 9% for ACEFLow; P = 0.017) and CSS (25% for CSSHigh vs. 12% for CSSMid vs. 8% for CSSLow; P = 0.008). The predictive accuracy for both ACEF and CSS was moderate (c-statistics, 0.629 and 0.638, respectively). CONCLUSION: Both ACEF and CSS predict with moderate accuracy MACE at 1-year in patients with heavily calcified coronary stenosis undergoing rotational atherectomy with stent implantation.
Pyxaras et al. (Wed,) conducted a cohort in stable angina with heavily calcified coronary stenosis (n=221). High ACEF and Clinical SYNTAX (CSS) scores vs. Low and mid tertiles of ACEF and CSS scores was evaluated on MACE at one-year (composite of cardiac death, myocardial infarction, and target vessel revascularization) (p=0.017). High ACEF and Clinical SYNTAX scores predicted higher 1-year MACE rates (24% vs 9%, P=0.017 for ACEF; 25% vs 8%, P=0.008 for CSS) in patients undergoing rotational atherectomy with stenting.
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