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TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells | Synapse

September 6, 2012BMC Cancer101 citationsOpen Access

TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells

LFLionel Flamant EREdith Roegiers MSMichael St.Pierre

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Abstract

Altogether, our results unravel a new mechanism for taxol and etoposide resistance mediated by TMEM45A. High levels of TMEM45A expression in tumors may be indicative of potential resistance to cancer therapy, making TMEM45A an interesting biomarker for resistance.

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Cite This Study

Flamant et al. (2012) studied this question.

synapsesocial.com/papers/69d7c4caf39344339dd1812e https://doi.org/https://doi.org/10.1186/1471-2407-12-391

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