October 30, 2013Open Access
Clinical implications of new-onset left bundle branch block after transcatheter aortic valve replacement: analysis of the PARTNER experience
Structured PICO
Does new-onset LBBB after TAVR worsen clinical outcomes (death, hospitalization, stroke, MI) at 1 year in patients without baseline intraventricular conduction delay?
P
Population
Patients without intraventricular baseline conduction who underwent transcatheter aortic valve replacement (TAVR) in the PARTNER experience
I
Intervention
New-onset left bundle branch block (LBBB) after TAVR
C
Comparator
No new-onset LBBB after TAVR
O
Outcome
Death, repeat hospitalization, stroke, or myocardial infarction at 1 yearhard clinical
New-onset LBBB after TAVR does not increase 1-year mortality or hard ischemic events, but increases the need for permanent pacemakers and blunts LVEF recovery.
Abstract
Persistent, new-onset LBBB occurred in 10.5% of patients without intraventricular baseline conduction who underwent TAVR in the PARTNER experience. New LBBB was not associated with death, repeat hospitalization, stroke, or myocardial infarction at 1 year, but was associated with a higher rate of PPI and failure of left ventricular ejection fraction to improve.
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Authors
Tamim Nazif
Interventional Cardiology
M
Mathew Williams
Valdosta State University
Rebecca T. Hahn
Structural Heart Disease
Journals
European Heart Journal
Actions
Institutions
Columbia University Irving Medical Center
References and Citations
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