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Active smokers and those exposed to secondhand smoke are at increased risk of bacterial infection. Tobacco smoke exposure increases susceptibility to respiratory tract infections, including tuberculosis, pneumonia and Legionnaires disease; bacterial vaginosis and sexually transmitted diseases, such as chlamydia and gonorrhoea; Helicobacter pylori infection; periodontitis; meningitis; otitis media; and post-surgical and nosocomial infections. Tobacco smoke compromises the anti-bacterial function of leukocytes, including neutrophils, monocytes, T cells and B cells, providing a mechanistic explanation for increased infection risk. Further epidemiological, clinical and mechanistic research into this important area is warranted.
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Juhi Bagaitkar
Donald R. Demuth
David A. Scott
Tobacco Induced Diseases
University of Louisville
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Bagaitkar et al. (Tue,) studied this question.
www.synapsesocial.com/papers/6a17923ecf49e78c48b4355d — DOI: https://doi.org/10.1186/1617-9625-4-12