July 16, 2015

Small Organoselenium Compounds: More than just Glutathione Peroxidase Mimics

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Abstract

Se-ing and doing: Isoselenazoles are novel, very potent antioxidant derivatives offering remarkable cytoprotection to human cells. Synthetically available in only a few steps, these compounds have the potential to fight diseases caused by oxidative stress.

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Thomas Wirth (Thu,) studied this question.

synapsesocial.com/papers/6a1f3308019c3aaee5832a63 — DOI: https://doi.org/10.1002/anie.201505056

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

The Refined Structure of the Selenoenzyme Glutathione Peroxidase at 0.2‐nm Resolution· 1983 · 685 citations
Unusually Short Chalcogen Bonds Involving Organoselenium: Insights into the Se–N Bond Cleavage Mechanism of the Antioxidant Ebselen and Analogues· 2015 · 104 citations
Organoselenium chemistry. Redox chemistry of selenocysteine model systems· 1987 · 172 citations
CHAPTER 10.2. Current Research on Mimics and Models of Selenium‐Containing Antioxidants· 2013 · 9 citations
The need for selenite and molybdate in the formation of formic dehydrogenase by members of the <i>Coli-aerogenes</i> group of bacteria· 1954 · 257 citations

Authors

Thomas Wirth

Cardiff University

Journals

Angewandte Chemie International Edition

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Cardiff University

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Small Organoselenium Compounds: More than just Glutathione Peroxidase Mimics

Key Points

Abstract

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Discussion

Cite this study

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Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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