High-temporal-resolution tissue phase mapping identified significant age-related changes in peak and time-to-peak left ventricular myocardial velocities in radial and long-axis directions.
Cross-Sectional (n=59)
Can high-temporal-resolution tissue phase mapping identify local changes in myocardial velocities associated with different age groups and left ventricular pathology?
High-temporal-resolution tissue phase mapping combined with a multisegment visualization model effectively identifies local changes in myocardial velocities associated with aging and left ventricular pathology.
PURPOSE: To apply high-temporal-resolution tissue phase mapping (TPM) to derive a detailed representation of normal regional myocardial motion in a large cohort of 58 normal subjects (three age groups) and one patient with dilated cardiomyopathy. MATERIALS AND METHODS: Analysis included transformation of the acquired myocardial velocities into radial, circumferential, and long-axis motion components representing left ventricular (LV) function with a spatiotemporal resolution of 1.3 x 2.6 x 8 mm(3) and 13.8 msec, respectively. To compare multidirectional regional myocardial velocities between groups of subjects, a multisegment and multislice visualization model was employed. Regional myocardial motion was mapped onto the visualization model to display the current status of myocardial motion from base to apex as in-plane velocity vector fields in conjunction with color-coded long-axis plane motion. Moreover, correlation analysis was used to investigate regional differences in myocardial dynamics. RESULTS: Age-related changes in LV myocardial velocities resulted in significant differences of peak and time-to-peak velocities in the radial and long-axis directions. Correlation analysis revealed clearly visible regional differences in the temporal evolution of long-axis and circumferential velocities, particularly between the youngest and oldest age groups. Comparison of pathological LV motion with age-matched volunteers indicated marked regional alterations in myocardial velocities and dynamics. CONCLUSION: High-temporal-resolution TPM in combination with a schematic visualization model and correlation analysis permits the identification of local changes in myocardial velocities associated with different age groups and a common LV pathology.
Föll et al. (Wed,) conducted a cross-sectional in Normal subjects and dilated cardiomyopathy (n=59). High-temporal-resolution tissue phase mapping (TPM) vs. Different age groups and age-matched volunteers was evaluated on Regional myocardial velocities and dynamics (radial, circumferential, and long-axis motion components). High-temporal-resolution tissue phase mapping identified significant age-related changes in peak and time-to-peak left ventricular myocardial velocities in radial and long-axis directions.