Early repolarization with a horizontal ST segment was significantly more frequent in survivors of sudden cardiac arrest compared to matched controls (20% vs. 3.3%; p=0.021).
Case-Control (n=85)
Is early repolarization with a horizontal ST segment associated with aborted sudden cardiac arrest in patients without structural heart disease?
Early repolarization with a horizontal ST segment is significantly more prevalent in survivors of sudden cardiac arrest without structural heart disease, suggesting its value as a marker for malignant early repolarization.
Absolute Event Rate: 20% vs 3.3%
p-value: p=0.021
BACKGROUND: Risk stratification of the early repolarization pattern (ERP) is needed to identify malignant early repolarization. J-point elevation with a horizontal ST segment was recently suggested as a malignant feature of the ERP. In this study, the prevalence of the ERP with a horizontal ST segment was examined among survivors of sudden cardiac arrest (SCA) without structural heart disease to evaluate the value of ST-segment morphology in risk stratification of the ERP. METHODS: We reviewed the data of 83 survivors of SCA who were admitted from August 2005 to August 2010. Among them, 25 subjects without structural heart disease were included. The control group comprised 60 healthy subjects who visited our health promotion center; all control subjects were matched for age, sex, and underlying disease (diabetes mellitus, hypertension). Early repolarization was defined as an elevation of the J point of at least 0.1 mV above the baseline in at least two continuous inferior or lateral leads that manifested as QRS slurring or notching. An ST-segment pattern of 2 mm (p = 0.025). Four SCA subjects (16%) and one (1.7%) control subject had an ERP in the inferior lead (p = 0.025). CONCLUSION: The prevalence of ERP with a horizontal ST segment was higher in patients with aborted SCA than in matched controls. This result suggests that ST morphology has value in the recognition of malignant early repolarization.
Kim et al. (Sat,) conducted a case-control in Sudden cardiac arrest (n=85). Early repolarization with horizontal ST segment vs. Healthy matched controls was evaluated on Prevalence of early repolarization with a horizontal ST segment (p=0.021). Early repolarization with a horizontal ST segment was significantly more frequent in survivors of sudden cardiac arrest compared to matched controls (20% vs. 3.3%; p=0.021).
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