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The instability of a breast cancer subtyping scheme like PAM50 could have important consequences in clinical management of patients. AIMS is a fully stable and robust subtyping scheme that recapitulates PAM50.
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Éric R. Paquet
Université Laval
Michael Hallett
Western University
JNCI Journal of the National Cancer Institute
McGill University
McGill University Health Centre
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Paquet et al. (Thu,) studied this question.
synapsesocial.com/papers/69dee50692a5e9426ae93cca — DOI: https://doi.org/10.1093/jnci/dju357