Critical Assessment of Pharmaceutical ProcessesA Rationale for Changing the Synthetic Route

ADVERTISEMENT RETURN TO ISSUEPREVArticleCritical Assessment of Pharmaceutical ProcessesA Rationale for Changing the Synthetic RouteMike Butters, David Catterick, Andrew Craig, Alan Curzons, David Dale, Adam Gillmore, Stuart P. Green, Ivan Marziano, Jon-Paul Sherlock, and Wesley WhiteView Author Information AstraZeneca, Process R&D, Avlon/Charnwood, Avlon Works, Severn Road, Hallen, Bristol BS10 7ZE, U.K., GlaxoSmithKline, Synthetic Chemistry, Old Powder Mills, Tonbridge, Kent TN11 9AN, U.K., and Pfizer, Chemical R&D, PGR&D, Ramsgate Road, Sandwich, Kent CT13 9NJ, U.K. Cite this: Chem. Rev. 2006, 106, 7, 3002–3027Publication Date (Web):March 8, 2006Publication History Received25 August 2005Published online8 March 2006Published inissue 1 July 2006https://pubs.acs.org/doi/10.1021/cr050982whttps://doi.org/10.1021/cr050982wresearch-articleACS PublicationsCopyright © 2006 American Chemical SocietyRequest reuse permissionsArticle Views8773Altmetric-Citations186LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Impurities,Manufacturing,Materials,Safety,Separation science Get e-Alerts