Key points are not available for this paper at this time.
We provide a review on the status of theoretical modeling of tautomerization in free-base porphyrin. We focus our discussion on several aspects, namely: (1) potential surfaces for both the stepwise and concerted mechanisms calculated at different levels of theory, (2) solvent effects and (3) kinetics. The importance of quantum mechanical tunneling in this double hydrogen atoms transfer process is analyzed.
Maity et al. (Thu,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: