December 30, 2003

Association between different measurements of obesity and the incidence of hypertension

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Hypertension (n=592). Intervention: Waist circumference and body mass index vs. Normal waist circumference and body mass index. Primary outcome: Incidence of hypertension (HR 1.72, 95% CI 1.09-2.73, p=0.02).

Key Result

Obesity defined by higher waist circumference was a better predictor of incident hypertension than body mass index, significantly increasing risk in women (HR 1.72; 95% CI 1.09-2.73; P=0.02).

Study Design

Type

Cohort (n=592)

PICO

Population

Hypertension (n=592)

Intervention / Comparator

Waist circumference and body mass index vs Normal waist circumference and body mass index

Primary Outcome

Incidence of hypertension — HR 1.72 (1.09-2.73), p=0.02

Main Result

Effect estimate: HR 1.72 (95% CI 1.09-2.73)

p-value: p=0.02

Abstract

BACKGROUND: Obesity is a risk factor for the incidence of hypertension, but it is still unclear whether this risk can be better estimated by body mass index (BMI) or waist circumference (WC). METHODS: In the baseline evaluation of a population-based cohort, 1089 adults answered a pretested questionnaire and had their baseline blood pressure (BP) and anthropometric measurements assessed according to standardized recommendations. Excluding the individuals with hypertension at baseline, and those deceased or lost during the follow-up, 592 individuals (80.5% of those eligible) were visited again. Obesity was defined as BMI >/=30 kg/m(2) for both genders, and WC >/=102 cm for men and WC >/=88 cm for women. Incident cases of hypertension were characterized by BP >/=140/90 mm Hg or use of BP medication in the follow-up visit. RESULTS: After a mean follow-up of 5.6 +/- 1.1 years, 127 incident cases of hypertension were identified. The hazard ratios (Cox model), adjusted for age and baseline systolic BP (95% CI and P), for BMI higher than 30 kg/m(2) were 1.08 (0.52-2.24, P =.82) in men and 1.74 (0.93-3.26, P =.08) in women. The corresponding figures were 1.78 (0.76-4.09, P =.18) for men with WC >/=102, and 1.72 (1.09-2.73, P =.02) for women with WC >/=88 cm. CONCLUSIONS: We conclude that the risk for hypertension may be better identified by obesity defined by higher WC than higher BMI.

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Cite This Study

Miguel Gus (Tue,) conducted a cohort in Hypertension (n=592). Waist circumference and body mass index vs. Normal waist circumference and body mass index was evaluated on Incidence of hypertension (HR 1.72, 95% CI 1.09-2.73, p=0.02). Obesity defined by higher waist circumference was a better predictor of incident hypertension than body mass index, significantly increasing risk in women (HR 1.72; 95% CI 1.09-2.73; P=0.02).

synapsesocial.com/papers/6a1d9e6633e2df9c962fcaea https://doi.org/https://doi.org/10.1016/j.amjhyper.2003.08.010

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