Epidemiology of Invasive Streptococcus pneumoniae Infections in the United States, 1995-1998Opportunities for Prevention in the Conjugate Vaccine Era

Young children, elderly persons, and black persons of all ages are disproportionately affected by invasive pneumococcal disease. Current ACIP recommendations do not address a subset of persons aged 18 to 64 years but do include those at highest risk for death from invasive pneumococcal disease.