Do biomechanical tools improve individualized rupture risk estimation for abdominal aortic aneurysms compared to standard diameter and growth rate criteria?
Biomechanical tools, including advanced imaging and computational modeling, offer potential for more individualized and accurate abdominal aortic aneurysm rupture risk estimation beyond traditional diameter criteria.
Abdominal aortic aneurysms are a common health problem and currently the need for surgical intervention is determined based on maximum diameter and growth rate criteria. Since these universal variables often fail to predict accurately every abdominal aortic aneurysms evolution, there is a considerable effort in the literature for other markers to be identified towards individualized rupture risk estimations and growth rate predictions. To this effort, biomechanical tools have been extensively used since abdominal aortic aneurysm rupture is in fact a material failure of the diseased arterial wall to compensate the stress acting on it. The peak wall stress, the role of the unique geometry of every individual abdominal aortic aneurysm as well as the mechanical properties and the local strength of the degenerated aneurysmal wall, all confer to rupture risk. In this review article, the assessment of these variables through mechanical testing, advanced imaging and computational modeling is reviewed and the clinical perspective is discussed.
Kontopodis et al. (Tue,) studied this question.
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