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Population data raise concerns about the validity of the current safe intake level that uses the kidney as the sole target in assessing the health risk from ingested cadmium. The data also question the validity of incorporating the default 5% absorption rate in the threshold-type risk assessment model, known as the provisional tolerable weekly intake (PTWI), to derive a safe intake level for cadmium.
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Soisungwan Satarug
Scott H. Garrett
Mary Ann Sens
Environmental Health Perspectives
University of North Dakota
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Satarug et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69daa7d73bc1ef722568468e — DOI: https://doi.org/10.1289/ehp.0901234
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