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Editorials1 February 1990Does Increased Blood Pressure Cause Left Ventricular Hypertrophy or Vice Versa?Richard B. DevereuxRichard B. DevereuxAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-112-3-157 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHypertension is a primary risk factor for cardiac and cerebrovascular disease, but the incidence of morbid events in patients with hypertension of average severity is relatively low and poorly predicted by blood pressure level (1). Furthermore, successful reduction of arterial pressure by standard antihypertensive drugs prevents less than half of the morbidity attributable to hypertension (2, 3). Perhaps attention has been disproportionately focused on identifying and controlling increased blood pressure rather than on recognizing and managing hypertensive heart disease.It has long been known that among hypertensive patients no matter what their blood pressure, complications occur more frequently in those...References1. Alderman M. The epidemiology of hypertension: etiology, natural history and the impact of therapy. Cardiovascular Reviews and Reports. 1980;1:509-19. Google Scholar2. CutlerMacMahonFurberg JSC. Controlled clinical trials of drug treatment for hypertension. A review. Hypertension. 1989;13(Suppl I):36-44. CrossrefMedlineGoogle Scholar3. MacMahonCutlerStamler SJJ. Antihypertensive drug treatment. Potential, expected, and observed effects on stroke and on coronary heart disease. Hypertension. 1989;13(Suppl I):45-50. CrossrefGoogle Scholar4. DevereuxCasaleWallerson RPD. 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DevereuxPickeringHarshfield RTG. Left ventricular hypertrophy in patients with hypertension: importance of blood pressure response to regularly recurring stress. Circulation. 1983;68:470-6. CrossrefMedlineGoogle Scholar10. MesserliSundgaard-RiiseReisin FKE. Dimorphic cardiac adaptation to obesity and arterial hypertension. Arch Intern Med. 1983;99:757-61. AbstractGoogle Scholar11. HammondDevereuxAldermanLaragh IRMJ. Relation of blood pressure and body build to left ventricular mass in normotensive and hypertensive employed adults. J Am Coll Cardiol. 1988;12:996-1004. CrossrefMedlineGoogle Scholar12. SchmiederMesserliGaravagliaNunez RFGB. Dietary salt intake. A determinant of cardiac involvement in essential hypertension. Circulation. 1988;78:951-6. CrossrefMedlineGoogle Scholar13. DevereuxDrayerChien RJS. Whole blood viscosity as a determinant of cardiac hypertrophy in systemic hypertension. Am J Cardiol. 1984;54:592-5. CrossrefMedlineGoogle Scholar14. GanauDevereuxPickering ART. 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Hypertension. 1988;12:206-13. CrossrefMedlineGoogle Scholar19. NielsenOxhoj JH. Echocardiographic variables in progeny of hypertensive and normotensive parents. Acta Med Scand. 1985;693(Suppl):61-4. CrossrefGoogle Scholar20. RadiceAlliAvanzini MCF. Left ventricular structure and function in normotensive adolescents with a genetic predisposition to hypertension. Am Heart J 1986;111:115-20. CrossrefMedlineGoogle Scholar21. deLeonardisDe ScalziFalchetti VMA. Echocardiographic evaluation of children with and without family history of essential hypertension. Am J Hypertens. 1988;1:305-8. CrossrefMedlineGoogle Scholar22. deSimoneDevereuxSchlusselRomanAldermanLaragh GRYMMJ. Echocardiographic left ventricular mass predicts risk of developing subsequent borderline hypertension Abstract. J Am Coll Cardiol. 1990;15: In press. Google Scholar23. FagardVan der BroekeBielenAmery RCEA. Maximum oxygen uptake and cardiac size and function in twins. Am J Cardiol. 1987;60:1362-7. CrossrefMedlineGoogle Scholar24. HarshfieldGrimSavageAndersonHwang GCDSC. Heritability of echocardiographically determined left ventricular mass index independent of hypertension in black twins Abstract. Circulation. 1988;78(Suppl II):228. Google Scholar25. GottdienerBrownZoltickFletcher JJJR. Left ventricular pressure in men with normal blood pressure: relation to exaggerated blood pressure response to exercise. Ann Intern Med. 1990;112:161-166. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York Hospital-Cornell Medical Center New York, New York Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByEffect of Intensive Blood Pressure Reduction on Left Ventricular Mass, Structure, Function, and Fibrosis in the SPRINT-HEARTLack of Reduction of Left Ventricular Mass in Treated Hypertension: The Strong Heart StudyProlonged QT Interval Is Associated with Blood Pressure Rather Than Left Ventricular Mass in Spontaneously Hypertensive RatsRetinal Arteriolar Diameter and Risk for HypertensionTien Yin Wong, MD, PhD, Ronald Klein, MD, MPH, A. Richey Sharrett, MD, DrPH, Bruce B. Duncan, MD, PhD, David J. Couper, PhD, Barbara E.K. Klein, MD, MPH, Larry D. Hubbard, MAT, and F. 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Role of prostaglandins and sodium-lithium countertransport activitySodium-lithium countertransport and cardiorenal abnormalities in essential hypertension.Diabetes mellitus and hypertension: A physiologic basis for a rational therapeutic approachUltrasound characterization of myocardial hypertrophyHypertension and ischemic heart disease: The challenge of the 1990s 1 February 1990Volume 112, Issue 3Page: 157-159KeywordsBlood pressureBurnsCardiovascular therapyCerebrovascular diseasesDrugsHeart diseasesHypertensionLeft ventricular hypertrophyMedical risk factorsMorbidity Issue Published: 1 February 1990 PDF DownloadLoading ...
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Richard B. Devereux
Boston University
Annals of Internal Medicine
Cornell University
NewYork–Presbyterian Hospital
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Richard B. Devereux (Thu,) studied this question.
synapsesocial.com/papers/6a1a797449c6765e38858229 — DOI: https://doi.org/10.7326/0003-4819-112-3-157