Local factors regulating vasomotor tone and organ blood flow include myogenic and metabolic autoregulation, flow-mediated responses, and vasoactive substances released from red blood cells.
Organ blood flow is determined by perfusion pressure and vasomotor tone in the resistance vessels of the organ. Local factors that regulate vasomotor tone include myogenic and metabolic autoregulation, flow-mediated and conducted responses, and vasoactive substances released from red blood cells. The relative importance of each of these factors varies over time, from tissue to tissue, and among vessel generations.
Philip S. Clifford (Tue,) conducted a review in Blood flow regulation. Local factors regulating vasomotor tone and organ blood flow include myogenic and metabolic autoregulation, flow-mediated responses, and vasoactive substances released from red blood cells.