Three male patients with spontaneous or inducible VF, J waves, and ST elevation in inferior leads showed augmented ST elevation after disopyramide injection, suggesting a Brugada syndrome variant.
Case Report (n=3)
INTRODUCTION: The clinical characteristics of three patients with spontaneous or inducible ventricular fibrillation (VF) without apparent heart disease, who presented with J wave and ST segment elevation in inferior leads, are described. METHODS AND RESULTS: All patients were male and experienced syncope. Their symptoms occurred at night or early in the morning. Holter ECG revealed infrequent premature ventricular complexes. Injection with disopyramide 2 mg/kg augmented ST segment elevation. CONCLUSION: These characteristics were very similar to those of patients with Brugada syndrome. These three patients with these specific features might have a variant of Brugada syndrome.
TAKAGI et al. (Tue,) conducted a case report in Ventricular fibrillation without apparent heart disease (n=3). Disopyramide was evaluated on ST segment elevation. Three male patients with spontaneous or inducible VF, J waves, and ST elevation in inferior leads showed augmented ST elevation after disopyramide injection, suggesting a Brugada syndrome variant.