Atrial fibrillation was significantly associated with left atrial thrombus compared to sinus rhythm in tight rheumatic mitral stenosis (60.5% vs 39.5% of thrombus cases; p<0.0001).
Observational (n=250)
What are the clinical and echocardiographic predictors of left atrial thrombus in patients with tight rheumatic mitral stenosis?
Atrial fibrillation is a strong clinical predictor of left atrial thrombus in tight rheumatic mitral stenosis, and TEE is superior to TTE for its detection.
Absolute Event Rate: 60.5% vs 39.5%
p-value: p=<0.0001
Results: Two hundred and fifty consecutive patients having tight rheumatic mitral stenosis were studied. The mean age of the study population was 26.9 ± 7.5 years. There were more female 128 (51.2%) patients than males 122 (48.8%). Atrial fibrillation (AF) was present less frequently in the study as 33 (13.2%) patients had AF as compared to 217 (86.8%) patients having sinus rhythm. AF was more significantly associated with thrombus formation with 23 (60.5%) patients having thrombus as compared to 15 (39.5%) patients in sinus rhythm having thrombus p < 0.0001. Thrombus in LA was more commonly visualized on TEE as compared to TTE (X 2 =242.3, p=0.0001) and was mostly detected in left atrial appendage (X 2 =211.2, p=0.0001). Spontaneous echo contrast was visualized more frequently on TEE as compared to TTE in both the groups p<0.001.
Ali et al. (Thu,) conducted a observational in Rheumatic Mitral Stenosis (n=250). Atrial fibrillation vs. Sinus rhythm was evaluated on Left atrial thrombus formation (p=<0.0001). Atrial fibrillation was significantly associated with left atrial thrombus compared to sinus rhythm in tight rheumatic mitral stenosis (60.5% vs 39.5% of thrombus cases; p<0.0001).
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