Quantifying Risk in Sepsis: A Review of Illness Severity and Organ Dysfunction Scoring

Well-established clinical risk factors in sepsis include adequacy of antibiotics, presence of underlying disease, source and type of infection, and the presence of shock with MOF. The heterogeneous nature of patients with sepsis and difficulty in reliably describing their disease burden has led to the development of illness severity scoring systems that can be a useful tool for clinicians and investigators.