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Taken together here we suggest that the exposure of the chemoresistant cells in the tumor microenvironment leads to substantial alterations and might lead to promotion of acquired microenvironment-mediated chemoresistance and stemness.
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Svetlana Skolekova
Miroslava Matúšková
Martin Boháč
Cell Communication and Signaling
Palacký University Olomouc
Slovak Academy of Sciences
Comenius University Bratislava
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Skolekova et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d721a63f906f6a06bef4b1 — DOI: https://doi.org/10.1186/s12964-016-0127-0