The luteal phase was associated with significantly lower SDNN (136 vs. 154 ms; p=0.015) and SDANN (122 vs. 142 ms; p=0.004) compared to the follicular phase in healthy women.
Observational (n=30)
Does the luteal phase compared to the follicular phase alter heart rate variability and heart rate recovery in healthy women?
The luteal phase of the menstrual cycle is associated with lower SDNN and SDANN compared to the follicular phase, suggesting enhanced sympathetic activity.
Absolute Event Rate: 136% vs 154%
p-value: p=0.015
OBJECTIVE: The purpose of the present study was to investigate autonomic tone during the follicular and luteal phases of the menstrual cycle using heart rate variability (HRV) and heart rate recovery (HRR) in healthy women. SUBJECTS AND METHODS: Thirty women aged 22-37 years with regular menstrual cycles were included in the study. The HRV and HRR were measured at the follicular and luteal phases. The HRV was obtained using the time domain method with 24-hour long-term recordings. For time domain analysis, the following were obtained: standard deviation of all normal sinus R-R intervals during 24 h (SDNN), mean of the standard deviation of all normal sinus R-R intervals for all 5-min segments (SDNN index), standard deviation of average normal sinus R-R intervals for all 5-min segments (SDANN), root mean square of the successive normal sinus R-R interval difference (rMSSD), and percentage of successive normal sinus R-R intervals longer than 50 ms (pNN50). The HRR was calculated at the first, second, and third minute of recovery after the cessation of peak exercise using a treadmill test. The paired sample t test was used for the comparison of both phases of the menstrual cycle. RESULTS: The SDNN (136 ± 39 vs. 154 ± 32 ms; p = 0.015) and SDANN (122 ± 36 vs. 142 ± 36 ms; p = 0.004) were significantly lower during the luteal phase than during the follicular phase. The HRR, rMSSD, and pNN50 were not different between the 2 phases. CONCLUSION: Parasympathetic tone markers of HRV and HRR were unaffected by the menstrual phase. Lower SDNN and SDANN during the luteal phase than during the follicular phase could have resulted from enhanced sympathetic activity during the luteal phase.
Yazar et al. (Fri,) conducted a observational in Healthy women (n=30). Luteal phase vs. Follicular phase was evaluated on SDNN (standard deviation of all normal sinus R-R intervals during 24 h) (p=0.015). The luteal phase was associated with significantly lower SDNN (136 vs. 154 ms; p=0.015) and SDANN (122 vs. 142 ms; p=0.004) compared to the follicular phase in healthy women.
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