Are increased concentrations of remnant cholesterol associated with increased all-cause mortality in patients with ischemic heart disease?
5414 patients with ischemic heart disease
Increased concentrations of calculated and measured remnant cholesterol (exposure)
All-cause mortalityhard clinical
Increased remnant cholesterol, rather than measured LDL cholesterol, explains part of the residual risk of all-cause mortality in patients with ischemic heart disease.
Increased concentrations of both calculated and measured remnant cholesterol were associated with increased all-cause mortality in patients with ischemic heart disease, which was not the case for increased concentrations of measured LDL cholesterol. This suggests that increased concentrations of remnant cholesterol explain part of the residual risk of all-cause mortality in patients with ischemic heart disease.
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Anne-Marie K Jepsen
Anne Langsted
Anette Varbo
Clinical Chemistry
University of Copenhagen
Rigshospitalet
Copenhagen University Hospital
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Jepsen et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69d7ba8a3b601d7be3ae2989 — DOI: https://doi.org/10.1373/clinchem.2015.253757