Rat subcutaneous gas pockets closely reflect a tissue region's venous blood pO2 and pCO2, with tensions not appreciably different from tissue tensions estimated by interpolation.
Do rat subcutaneous gas pockets accurately estimate tissue and venous blood pO2 and pCO2?
Subcutaneous gas pockets in rats provide a reliable estimation of tissue and venous blood pO2 and pCO2.
This study appraises use of gas pockets for estimation of tissue pO 2 and pCO 2 . a) Tensions of O 2 and CO 2 in rat subcutaneous pockets in the constant composition state were compared with tissue tensions estimated by a special interpolation technique using the pockets; the two types of results were not appreciably different. b) Possible values for venous blood pO 2 and pCO 2 were estimated by a “blood r” curve; agreement between expected blood tensions and gas pocket tensions supports the hypothesis that pockets closely reflect a tissue region's venous blood. c) Initial composition adjustments after introduction of five different mixtures of O 2 , CO 2 , and N 2 into the pockets were studied; the results were used to illustrate some theoretical properties of gas pockets in the body. Submitted on April 23, 1962
Hugh D. Van Liew (Thu,) conducted a other in Tissue pO2 and pCO2 estimation. Subcutaneous gas pockets vs. Tissue tensions estimated by interpolation technique was evaluated on Tensions of O2 and CO2. Rat subcutaneous gas pockets closely reflect a tissue region's venous blood pO2 and pCO2, with tensions not appreciably different from tissue tensions estimated by interpolation.