Does immunosuppressive therapy improve ventricular function or reduce mortality in patients with myocarditis?
Patients with myocarditis
Immunosuppressive drugs
No immunosuppressive therapy
Ventricular function and long-term mortality
Routine treatment of myocarditis with immunosuppressive drugs is not supported, as it does not provide additional benefit for ventricular function.
Our results do not support routine treatment of myocarditis with immunosuppressive drugs. Ventricular function improved regardless of whether patients received immunosuppressive therapy, but long-term mortality was high. Patients with a vigorous inflammatory response had less severe disease.
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Jay W. Mason
John B. OʼConnell
Ahvie Herskowitz
New England Journal of Medicine
Stanford University
Johns Hopkins University
University of British Columbia
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Mason et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69effb364f6a06657c21e37a — DOI: https://doi.org/10.1056/nejm199508033330501