Hemodynamic indices originating from pulsatile pressure should be considered alongside systolic and diastolic blood pressure to better assess cardiovascular risk and hypertensive end-organ damage.
Systolic and diastolic blood pressures are the exclusive mechanical factors usually considered as predictors of cardiovascular risk in populations of normotensive and hypertensive subjects at large. However, if hypertension is considered as a mechanical factor acting on the arterial wall with substantial deleterious consequences, the totality of the blood pressure curve should be considered in order to investigate the cardiovascular risk. The purpose of this review is to show that in addition to systolic and diastolic blood pressures, other hemodynamic indices that have particular relevance for cardiac complications and that originate from pulsatile pressure should be taken into account, with important consequences in cardiovascular epidemiology and in the pathophysiology of hypertensive end-organ damage.
Michel E. Safar (Sat,) conducted a review in Hypertension and cardiovascular risk. Pulsatile pressure indices (pulse pressure, arterial stiffness) vs. Systolic and diastolic blood pressure alone was evaluated. Hemodynamic indices originating from pulsatile pressure should be considered alongside systolic and diastolic blood pressure to better assess cardiovascular risk and hypertensive end-organ damage.