December 16, 1999Open Access
View Full PaperA Randomized Study of the Prevention of Sudden Death in Patients with Coronary Artery Disease
Structured PICO
Does electrophysiologically guided antiarrhythmic therapy with implantable defibrillators reduce sudden death in high-risk patients with coronary disease?
P
Population
High-risk patients with coronary disease
I
Intervention
Electrophysiologically guided antiarrhythmic therapy with implantable defibrillators
C
Comparator
Antiarrhythmic drugs
O
Outcome
Sudden deathhard clinical
Implantable defibrillators are effective in reducing sudden death in high-risk coronary disease patients, outperforming antiarrhythmic drugs.
Abstract
Electrophysiologically guided antiarrhythmic therapy with implantable defibrillators, but not with antiarrhythmic drugs, reduces the risk of sudden death in high-risk patients with coronary disease.