June 21, 2001Open Access
Comparison of Early Invasive and Conservative Strategies in Patients with Unstable Coronary Syndromes Treated with the Glycoprotein IIb/IIIa Inhibitor Tirofiban
Structured PICO
Does an early invasive strategy reduce major cardiac events in patients with unstable angina and NSTEMI treated with tirofiban?
P
Population
Patients with unstable angina and myocardial infarction without ST-segment elevation treated with the glycoprotein IIb/IIIa inhibitor tirofiban
I
Intervention
Early invasive strategy
C
Comparator
Conservative strategy
O
Outcome
Incidence of major cardiac eventscomposite
An early invasive strategy significantly reduces major cardiac events in patients with unstable angina and NSTEMI receiving glycoprotein IIb/IIIa inhibition.
Abstract
In patients with unstable angina and myocardial infarction without ST-segment elevation who were treated with the glycoprotein IIb/IIIa inhibitor tirofiban, the use of an early invasive strategy significantly reduced the incidence of major cardiac events. These data support a policy involving broader use of the early inhibition of glycoprotein IIb/IIIa in combination with an early invasive strategy in such patients.
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Authors
Christopher P. Cannon
Université Claude Bernard Lyon 1
William S. Weintraub
Interventional Cardiology
L
Laura A. Demopoulos
Inserm
Journals
New England Journal of Medicine
Actions
Institutions
Brigham and Women's Hospital
Emory University
Baylor College of Medicine
References and Citations
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