Are measles antibody titers elevated in the serum and cerebral spinal fluid of patients with multiple sclerosis compared to controls?
The finding of elevated measles antibodies in the serum and spinal fluid of patients with MS warrants continuing investigation into a potential relationship.
SummaryExamination of the sera of patients with multiple sclerosis by neutralization and complement-fixation tests revealed slightly higher antibody titers to measles virus than control subjects. The cerebral spinal fluid of patients with multiple sclerosis showed measurable antibody titers to measles virus in over 75% of the cases tested, whereas control subjects have shown no evidence of antibodies. The finding of elevated measles antibodies in the serum and spinal fluid of patients with MS does not imply or indicate a direct relationship but warrants continuing investigation.
Adams et al. (Sat,) studied this question.
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