Do beta-blockers and/or renin-angiotensin-aldosterone system inhibitors decrease blood pressure and improve arterial wall properties in patients with aortic disease?
Beta-blockers and RAAS inhibitors are recommended as preferential antihypertensive therapy in patients with aortic disease to improve arterial wall properties.
Hypertension, one of the major cardiovascular risk factors, promotes the formation of atheromatous lesions in the large arteries, including the aorta. It also favors aortic aneurysm and acute aortic syndrome such as aortic dissection or hematoma. In patients with aortic disease, beta-blockers and/or renin-angiotensin-aldosterone system inhibitors should be preferentially used to decrease blood pressure and improve arterial wall properties.
Baguet et al. (2011) studied this question.