June 27, 1996Open Access
Measurement of Fractional Flow Reserve to Assess the Functional Severity of Coronary-Artery Stenoses
Key Result
Myocardial fractional flow reserve (FFR) provides a reliable assessment of the functional severity of coronary-artery stenoses compared to noninvasive tests.
Structured PICO
Does myocardial fractional flow reserve (FFR) accurately assess the functional severity of moderate coronary-artery stenoses compared to noninvasive tests?
P
Population
Patients with coronary-artery stenoses of moderate severity
I
Intervention
Myocardial fractional flow reserve (FFR) calculated from pressure measurements during coronary arteriography
C
Comparator
Noninvasive tests commonly used to detect myocardial ischemia
O
Outcome
Usefulness of the index (FFR) to assess functional severity of coronary stenosessurrogate
Myocardial fractional flow reserve (FFR) is introduced as a new invasive index to assess the functional severity of moderate coronary stenoses compared to standard noninvasive ischemia testing.
Main Result
Absolute Event Rate: 0% vs 0%
Abstract
The clinical significance of coronary-artery stenoses of moderate severity can be difficult to determine. Myocardial fractional flow reserve (FFR) is a new index of the functional severity of coronary stenoses that is calculated from pressure measurements made during coronary arteriography. We compared this index with the results of noninvasive tests commonly used to detect myocardial ischemia, to determine the usefulness of the index.
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Authors
Nico H.J. Pijls
Interventional Cardiology
Bernard De Bruyne
Università Cattolica del Sacro Cuore
K
Kathinka Peels
Radboud University Nijmegen
Journals
New England Journal of Medicine
Actions
Institutions
Radboud University Nijmegen
Catharina Ziekenhuis
References and Citations
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