Multiple Sebaceous Neoplasms of the Skin: An Association with Multiple Visceral Carcinomas, Especially of the Colon

Five patients with multiple sebaceous neoplasms of the skin in association with multiple visceral cancers are reported. The visceral cancers involved particularly the gastrointestinal tract, and multiple adenocarcinomas of the colon were common. This report supports the concept that such a combination represents a syndrome. Another feature is the presence of squamoproliferative lesions of the skin. The likelihood is that the visceral cancers are of a low grade of malignancy.