Planar-Chiral Macrocyclic Host Pillar5arene: No Rotation of Units and Isolation of Enantiomers by Introducing Bulky Substituents

Enantiomers of bulky percyclohexylmethyl-substituted pillar5arene (Cy-C1-Pillar) were able to be separated by chiral column chromatography, and the separated enantiomers did not racemize. Even though modified with the bulky cyclohexylmethyl-substituents at both rims, Cy-C1-Pillar was able to capture a guest molecule.