January 30, 2015Open Access
View Full PaperHow Acute Total Sleep Loss Affects the Attending Brain: A Meta-Analysis of Neuroimaging Studies
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Abstract
Acute total sleep deprivation decreases brain activation in the fronto-parietal attention network (prefrontal cortex and intraparietal sulcus) and in the salience network (insula and medial frontal cortex). Increased thalamic activation after sleep deprivation may reflect a complex interaction between the de-arousing effects of sleep loss and the arousing effects of task performance on thalamic activity.