Does the withdrawal of digoxin carry risks for patients with chronic heart failure and impaired systolic function who are clinically stable on digoxin and ACE inhibitors?
Patients with chronic heart failure and impaired systolic function who have remained clinically stable while receiving digoxin and angiotensin-converting-enzyme inhibitors
Withdrawal of digoxin
Withdrawing digoxin from stable heart failure patients with impaired systolic function on ACE inhibitors poses considerable clinical risks.
These findings indicate that the withdrawal of digoxin carries considerable risks for patients with chronic heart failure and impaired systolic function who have remained clinically stable while receiving digoxin and angiotensin-converting-enzyme inhibitors.
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Milton Packer
Mihai Gheorghiade
James B. Young
New England Journal of Medicine
University of North Carolina at Chapel Hill
The Ohio State University
Baylor College of Medicine
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Packer et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d575155f8349d3f7ad4f9e — DOI: https://doi.org/10.1056/nejm199307013290101