Does cryoballoon ablation provide noninferior efficacy compared to radiofrequency ablation in patients with drug-refractory paroxysmal atrial fibrillation?
patients with drug-refractory paroxysmal atrial fibrillation
cryoballoon ablation
radiofrequency ablation
efficacy
Cryoballoon ablation is a safe and effective alternative to radiofrequency ablation, demonstrating noninferiority for the treatment of drug-refractory paroxysmal atrial fibrillation.
In this randomized trial, cryoballoon ablation was noninferior to radiofrequency ablation with respect to efficacy for the treatment of patients with drug-refractory paroxysmal atrial fibrillation, and there was no significant difference between the two methods with regard to overall safety. (Funded by Medtronic; FIRE AND ICE ClinicalTrials.gov number, NCT01490814.).
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Karl-Heinz Kuck
Josép Brugada
Alexander Fürnkranz
New England Journal of Medicine
Universitat de Barcelona
University of Milan
London School of Hygiene & Tropical Medicine
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Kuck et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69d56fb075589c71d767da8f — DOI: https://doi.org/10.1056/nejmoa1602014
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