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Sensitivity to painful thermal stimuli and willingness to report pain were studied in two experimental sessions. No treatment was given during the first session, but on the second session a placebo was administered as a potent, fast-acting analgesic. The placebo failed to affect sensitivity to thermal stimulation, but significant decreases in willingness to report pain were observed. A side effects questionnaire showed that a significant number of side effects were reported by subjects on the placebo session.
Feather et al. (Sat,) studied this question.