Subjects after acute myocardial infarction
Coronary vasodilator function in infarcted and normal myocardiumsurrogate
Acute myocardial infarction impairs coronary vasodilator function globally, affecting both infarcted and remote normal myocardium, which may impact the extent of ischemia and necrosis.
After acute myocardial infarction, there is a severe vasodilator abnormality involving not only resistance vessels in infarcted myocardium, but also those in myocardium perfused by normal coronary vessels. This dysfunction may affect the extent of myocardial ischemia and necrosis after coronary occlusion.
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Neal Uren
Tom Crake
David Lefroy
New England Journal of Medicine
Medical Research Council
Hammersmith Hospital
Cyclotron (Netherlands)
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Uren et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d74e8958d71cbec648f704 — DOI: https://doi.org/10.1056/nejm199407283310402